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Protein kinase C epsilon is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes

Protein kinase C (PKC) ε, a member of the novel PKC family, plays key roles in mitogenesis and survival in normal and cancer cells. PKCε is frequently overexpressed in epithelial cancers, particularly in lung cancer. Using a shRNA approach, here we established that PKCε is required for non-small cel...

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Detalhes bibliográficos
Main Authors: Caino, M. Cecilia, Haber, Cynthia Lopez, Kim, Jeewon, Mochly-Rosen, Daria, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432976/
https://ncbi.nlm.nih.gov/pubmed/21996750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.428
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