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Protein Kinase Cα Mediates Erlotinib Resistance in Lung Cancer Cells

Overexpression and mutational activation of the epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of non–small cell lung cancer (NSCLC). EGFR tyrosine-kinase inhibitors (TKIs) are given as a primary therapy for advanced patients with EGFR-activating mutations; howev...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharmacol
主要な著者: Abera, Mahlet B., Kazanietz, Marcelo G.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407729/
https://ncbi.nlm.nih.gov/pubmed/25724832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.097725
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