Φορτώνει......
Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
CYP2A13 is a human cytochrome P450 (P450) enzyme important in the bioactivation of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). CYP2A13 expression levels vary dramatically among lung biopsy samples from patients, presumably owing in part to a suppress...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Drug Metab Dispos |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407704/ https://ncbi.nlm.nih.gov/pubmed/25710941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.063305 |
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