Molecular conformation of the full-length tumor suppressor NF2/Merlin—a small angle neutron scattering study

The tumor suppressor protein Merlin inhibits cell proliferation upon establishing cell-cell contacts. Because Merlin has high sequence similarity to the Ezrin-Radixin-Moesin (ERM) family of proteins, the structural model of ERM protein autoinhibition and cycling between closed/resting and open/activ...

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Gepubliceerd in:J Mol Biol
Hoofdauteurs: Khajeh, Jahan Ali, Ju, Jeong Ho, Atchiba, Moussoubaou, Allaire, Marc, Stanley, Christopher, Heller, William T., Callaway, David J.E., Bu, Zimei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407695/
https://ncbi.nlm.nih.gov/pubmed/24882693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.05.011
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