Open Conformation of Ezrin Bound to Phosphatidylinositol 4,5-Bisphosphate and to F-actin Revealed by Neutron Scattering

Ezrin is a member of the ezrin-radixin-moesin family (ERM) of adapter proteins that are localized at the interface between the cell membrane and the cortical actin cytoskeleton, and they regulate a variety of cellular functions. The structure representing a dormant and closed conformation of an ERM...

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Autors principals: Jayasundar, Jayant James, Ju, Jeong Ho, He, Lilin, Liu, Dazhi, Meilleur, Flora, Zhao, Jinkui, Callaway, David J. E., Bu, Zimei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481312/
https://ncbi.nlm.nih.gov/pubmed/22927432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380972
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