Phosphatidylinositol 4,5-Bisphosphate Clusters the Cell Adhesion Molecule CD44 and Assembles a Specific CD44-Ezrin Heterocomplex, as Revealed by Small Angle Neutron Scattering

The cell adhesion molecule CD44 regulates diverse cellular functions, including cell-cell and cell-matrix interaction, cell motility, migration, differentiation, and growth. In cells, CD44 co-localizes with the membrane-cytoskeleton adapter protein Ezrin that links the CD44 assembled receptor signal...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Xiaodong, Khajeh, Jahan Ali, Ju, Jeong Ho, Gupta, Yogesh K., Stanley, Christopher B., Do, Changwoo, Heller, William T., Aggarwal, Aneel K., Callaway, David J. E., Bu, Zimei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358296/
https://ncbi.nlm.nih.gov/pubmed/25572402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589523
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