MicroRNA-30d and microRNA-181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling m...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jeon, Myung Jae, Kim, Eun Jae, Lee, Maria, Kim, Hoguen, Choi, Jong Rak, Chae, Hee Dong, Moon, Yeo Jung, Kim, Sei Kwang, Bai, Sang Wook
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407598/
https://ncbi.nlm.nih.gov/pubmed/25630974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12448
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