MicroRNA-30d and microRNA-181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling m...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Jeon, Myung Jae, Kim, Eun Jae, Lee, Maria, Kim, Hoguen, Choi, Jong Rak, Chae, Hee Dong, Moon, Yeo Jung, Kim, Sei Kwang, Bai, Sang Wook
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407598/
https://ncbi.nlm.nih.gov/pubmed/25630974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12448
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