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HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse

Pelvic organ prolapse (POP) is a common, debilitating disorder affecting millions of women. Uterosacral ligaments (USLs) are the main supportive structures of the uterus and vagina and are often attenuated in women with POP. Although the mechanical strength of USLs is known to be dependent on collag...

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Библиографические подробности
Главные авторы: Connell, Kathleen A., Guess, Marsha K., Chen, Heidi, Andikyan, Vaagn, Bercik, Richard, Taylor, Hugh S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242622/
https://ncbi.nlm.nih.gov/pubmed/18274672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34193
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