Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

Microphthalmia-associated transcription factor (MITF) is the master regulator of the melanocyte lineage. To understand how MITF regulates transcription, we used tandem affinity purification and mass spectrometry to define a comprehensive MITF interactome identifying novel cofactors involved in trans...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Laurette, Patrick, Strub, Thomas, Koludrovic, Dana, Keime, Céline, Le Gras, Stéphanie, Seberg, Hannah, Van Otterloo, Eric, Imrichova, Hana, Siddaway, Robert, Aerts, Stein, Cornell, Robert A, Mengus, Gabrielle, Davidson, Irwin
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2015
Ämnen:
Biochemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407272/
https://ncbi.nlm.nih.gov/pubmed/25803486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06857
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