Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells

MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling factor in melanoma cells. ShRNA-mediated silencing of the NURF subunit BPTF revealed its essential role in several melanoma cell lines and i...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Koludrovic, Dana, Laurette, Patrick, Strub, Thomas, Keime, Céline, Le Coz, Madeleine, Coassolo, Sebastien, Mengus, Gabrielle, Larue, Lionel, Davidson, Irwin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595011/
https://ncbi.nlm.nih.gov/pubmed/26440048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005555
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