TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation

The functions of the TAF subunits of mammalian TFIID in physiological processes remain poorly characterised. In this study, we describe a novel function of TAFs in directing genomic occupancy of a transcriptional activator. Using liver-specific inactivation in mice, we show that the TAF4 subunit of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Alpern, Daniil, Langer, Diana, Ballester, Benoit, Le Gras, Stephanie, Romier, Christophe, Mengus, Gabrielle, Davidson, Irwin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359380/
https://ncbi.nlm.nih.gov/pubmed/25209997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03613
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