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TAF4 inactivation in embryonic fibroblasts activates TGFβ signalling and autocrine growth
We have inactivated transcription factor TFIID subunit TBP-associated factor 4 (TAF4) in mouse embryonic fibroblasts. Mutant taf4(−/−) cells are viable and contain intact TFIID comprising the related TAF4b showing that TAF4 is not an essential protein. TAF4 inactivation deregulates more than 1000 ge...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1182243/ https://ncbi.nlm.nih.gov/pubmed/16015375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600748 |
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