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α-Synuclein Reduces Tension and Increases Undulations in Simulations of Small Unilamellar Vesicles

Using coarse-grained molecular dynamics simulations we have explored the effect of α-Synuclein (αSyn) on the structural and mechanical properties of small unilamellar vesicles in the fluid-phase. The study is motivated by observations that a high density of membrane-bound αSyn inhibits the fusion of...

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Publicat a:Biophys J
Autors principals: Braun, Anthony R., Sachs, Jonathan N.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407265/
https://ncbi.nlm.nih.gov/pubmed/25902424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.029
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