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Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents
The μ1 opioid receptor (OPRM1) genetic variant A118G results in decreased μ-receptor binding potential in the brain and increases morphine requirement. We hypothesized that OPRM1 A118G polymorphism will affect morphine-induced respiratory depression (MIRD) risk in children receiving morphine. A pros...
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| 出版年: | Pharmacogenomics J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406866/ https://ncbi.nlm.nih.gov/pubmed/25266679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.59 |
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