Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents

The μ1 opioid receptor (OPRM1) genetic variant A118G results in decreased μ-receptor binding potential in the brain and increases morphine requirement. We hypothesized that OPRM1 A118G polymorphism will affect morphine-induced respiratory depression (MIRD) risk in children receiving morphine. A pros...

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Bibliografski detalji
Izdano u:Pharmacogenomics J
Glavni autori: Chidambaran, V, Mavi, J, Esslinger, H, Pilipenko, V, Martin, LJ, Zhang, K, Sadhasivam, S
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406866/
https://ncbi.nlm.nih.gov/pubmed/25266679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.59
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