Cannabinoid Receptor 1 Promotes Hepatocellular Carcinoma Initiation and Progression via Multiple Mechanisms

Hepatocellular carcinoma (HCC) has high mortality and no adequate treatment. Endocannabinoids interact with hepatic CB1 receptors (CB1R) to promote hepatocyte proliferation in liver regeneration via inducing cell-cycle proteins involved in mitotic progression, including Forkhead Box M1 (FOXM1). Beca...

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Vydáno v:Hepatology
Hlavní autoři: Mukhopadhyay, Bani, Schuebel, Kornel, Mukhopadhyay, Partha, Cinar, Resat, Godlewski, Grzegorz, Xiong, Keming, Mackie, Ken, Lizak, Martin, Yuan, Qiaoping, Goldman, David, Kunos, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406817/
https://ncbi.nlm.nih.gov/pubmed/25580584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27686
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