Transcriptional Regulation of Cannabinoid Receptor-1 Expression in the Liver by Retinoic Acid Acting via Retinoic Acid Receptor-γ

Alcoholism can result in fatty liver that can progress to steatohepatitis, cirrhosis, and liver cancer. Mice fed alcohol develop fatty liver through endocannabinoid activation of hepatic CB(1) cannabinoid receptors (CB(1)R), which increases lipogenesis and decreases fatty acid oxidation. Chronic alc...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Bani, Liu, Jie, Osei-Hyiaman, Douglas, Godlewski, Grzegorz, Mukhopadhyay, Partha, Wang, Lei, Jeong, Won-Il, Gao, Bin, Duester, Gregg, Mackie, Ken, Kojima, Soichi, Kunos, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885177/
https://ncbi.nlm.nih.gov/pubmed/20410309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068460
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