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Chronic alcohol-induced hepatic insulin resistance and ER stress ameliorated by PPAR-δ agonist treatment
BACKGROUND: Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agon...
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| Veröffentlicht in: | J Gastroenterol Hepatol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406771/ https://ncbi.nlm.nih.gov/pubmed/22988930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1746.2012.07256.x |
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