PPARδ agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair

BACKGROUND/AIMS: Chronic ethanol exposure impairs liver regeneration due to inhibition of insulin signaling and oxidative injury. PPAR agonists function as insulin sensitizers and anti-inflammatory agents. We investigated whether treatment with a PPARδ agonist could restore hepatic insulin sensitivi...

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Главные авторы: Pang, Maoyin, de la Monte, Suzanne M., Longato, Lisa, Tong, Ming, He, Jiman, Chaudhry, Rajeeve, Duan, Kevin, Ouh, Jiyun, Wands, Jack R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680444/
https://ncbi.nlm.nih.gov/pubmed/19398227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.01.021
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