Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels

Meroterpenoid chrodrimanins, produced from Talaromyces sp. YO-2, are known to paralyze silkworm (Bombyx mori) larvae, but their target is unknown. We have investigated the actions of chrodrimanin B on ligand-gated ion channels of silkworm larval neurons using patch-clamp electrophysiology. Chrodrima...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Xu, Yan, Furutani, Shogo, Ihara, Makoto, Ling, Yun, Yang, Xinling, Kai, Kenji, Hayashi, Hideo, Matsuda, Kazuhiko
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406737/
https://ncbi.nlm.nih.gov/pubmed/25902139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122629
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