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A Fungal Metabolite Asperparaline A Strongly and Selectively Blocks Insect Nicotinic Acetylcholine Receptors: The First Report on the Mode of Action

Asperparalines produced by Aspergillus japonicus JV-23 induce paralysis in silkworm (Bombyx mori) larvae, but the target underlying insect toxicity remains unknown. In the present study, we have investigated the actions of asperparaline A on ligand-gated ion channels expressed in cultured larval bra...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hirata, Koichi, Kataoka, Saori, Furutani, Shogo, Hayashi, Hideo, Matsuda, Kazuhiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069973/
https://ncbi.nlm.nih.gov/pubmed/21483774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018354
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