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The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila

Nibbler (Nbr) is a 3′-to-5′ exonuclease that trims the 3′end of microRNAs (miRNAs) to generate different length patterns of miRNAs in Drosophila. Despite its effect on miRNAs, we lack knowledge of its biological significance and whether Nbr affects other classes of small RNAs such as piRNAs and endo...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Feltzin, Virzhiniya L, Khaladkar, Mugdha, Abe, Masashi, Parisi, Michael, Hendriks, Gert-Jan, Kim, Junhyong, Bonini, Nancy M
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406673/
https://ncbi.nlm.nih.gov/pubmed/25754031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12323
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