Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3′ ends in Drosophila

In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host genome. Piwi-interacting RNAs (piRNAs) of ∼23 to 30 nucleotides bound to PIWI clade Argonaute proteins silence transposons in a manner that is strictly dependent on their sequence complementarity. Hence, a k...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Wang, Hui, Ma, Zaijun, Niu, Kongyan, Xiao, Yi, Wu, Xiaofen, Pan, Chenyu, Zhao, Yun, Wang, Kai, Zhang, Yaoyang, Liu, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760310/
https://ncbi.nlm.nih.gov/pubmed/26718004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.128116
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