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The (not so) Immortal Strand Hypothesis

BACKGROUND: Non-random segregation of DNA strands during stem cell replication has been proposed as a mechanism to minimize accumulated genetic errors in stem cells of rapidly dividing tissues. According to this hypothesis, an “immortal” DNA strand is passed to the stem cell daughter and not the mor...

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Foilsithe in:Stem Cell Res
Main Authors: Tomasetti, Cristian, Bozic, Ivana
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405781/
https://ncbi.nlm.nih.gov/pubmed/25700960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.01.005
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