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Corticosteroids Augment BRAF Inhibitor Vemurafenib Induced Lymphopenia and Risk of Infection

We have previously demonstrated an impact of the BRAF inhibitor vemurafenib on patient lymphocyte counts. In the current study, the extent to which concomitant use of corticosteroids in BRAF inhibitor treated patients affects lymphocyte counts and predisposes to infection was investigated. A cohort...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sondermann, Wiebke, Griewank, Klaus G., Schilling, Bastian, Livingstone, Elisabeth, Leyh, Julia C., Rompoti, Natalia, Cosgarea, Ioana, Schimming, Tobias, Schadendorf, Dirk, Zimmer, Lisa, Hillen, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405567/
https://ncbi.nlm.nih.gov/pubmed/25897843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124590
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