Exposure to Endocrine Disruptor Induces Transgenerational Epigenetic Deregulation of MicroRNAs in Primordial Germ Cells

In mammals, germ cell differentiation is initiated in the Primordial Germ Cells (PGCs) during fetal development. Prenatal exposure to environmental toxicants such as endocrine disruptors may alter PGC differentiation, development of the male germline and induce transgenerational epigenetic disorders...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brieño-Enríquez, Miguel A., García-López, Jesús, Cárdenas, David B., Guibert, Sylvain, Cleroux, Elouan, Děd, Lukas, Hourcade, Juan de Dios, Pěknicová, Jana, Weber, Michael, del Mazo, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405367/
https://ncbi.nlm.nih.gov/pubmed/25897752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124296
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