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The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways
Foxp3(+) regulatory T (Treg) cells are essential to maintain immune homeostasis, yet controversy exists about the stability of this cell population. Bcl6-deficient (Bcl6(−/−)) mice develop severe and spontaneous T helper type 2 (Th2) inflammation and Bcl6-deficient Treg cells are ineffective at cont...
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| Pubblicato in: | Immunology |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405320/ https://ncbi.nlm.nih.gov/pubmed/25262912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12393 |
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