Goserelin for Ovarian Protection during Breast-Cancer Adjuvant Chemotherapy

BACKGROUND: Ovarian failure is a common toxic effect of chemotherapy. Studies of the use of gonadotropin-releasing hormone (GnRH) agonists to protect ovarian function have shown mixed results and lack data on pregnancy outcomes. METHODS: We randomly assigned 257 premenopausal women with operable hor...

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Publicat a:N Engl J Med
Autors principals: Moore, Halle C. F., Unger, Joseph M., Phillips, Kelly-Anne, Boyle, Frances, Hitre, Erika, Porter, David, Francis, Prudence A., Goldstein, Lori J., Gomez, Henry L., Vallejos, Carlos S., Partridge, Ann H., Dakhil, Shaker R., Garcia, Agustin A., Gralow, Julie, Lombard, Janine M., Forbes, John F., Martino, Silvana, Barlow, William E., Fabian, Carol J., Minasian, Lori, Meyskens, Frank L., Gelber, Richard D., Hortobagyi, Gabriel N., Albain, Kathy S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405231/
https://ncbi.nlm.nih.gov/pubmed/25738668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1413204
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