Combination Anastrozole and Fulvestrant in Metastatic Breast Cancer

BACKGROUND: The aromatase inhibitor anastrozole inhibits estrogen synthesis. Fulvestrant binds and accelerates degradation of estrogen receptors. We hypothesized that these two agents in combination might be more effective than anastrozole alone in patients with hormone-receptor (HR)–positive metast...

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Bibliografische gegevens
Hoofdauteurs: Mehta, Rita S., Barlow, William E., Albain, Kathy S., Vandenberg, Ted A., Dakhil, Shaker R., Tirumali, Nagendra R., Lew, Danika L., Hayes, Daniel F., Gralow, Julie R., Livingston, Robert B., Hortobagyi, Gabriel N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951300/
https://ncbi.nlm.nih.gov/pubmed/22853014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1201622
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