A Phase II Study of Imatinib Mesylate and Capecitabine in Metastatic Breast Cancer: Southwest Oncology Group Study 0338

PURPOSE: Imatinib mesylate is a potent inhibitor of the Bcr-Abl, c-kit, and platelet-derived growth factor receptor (PDGFR) tyrosine kinases. Based on variable expression of c-kit and PDGFR in breast cancer, and on in vitro data supporting synergy between imatinib and capecitabine, the Southwest Onc...

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Hauptverfasser: Chew, Helen K., Barlow, William E., Albain, Kathy, Lew, Danika, Gown, Allen, Hayes, Daniel F., Gralow, Julie, Hortobagyi, Gabriel N., Livingston, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510680/
https://ncbi.nlm.nih.gov/pubmed/19073506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3816/CBC.2008.n.062
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