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Screening for Clonal Hematopoiesis as a Predictive Marker for Development of Therapy-Related Myeloid Neoplasia (t-MN) Following Neoadjuvant Therapy for Breast Cancer (S0012): A Southwest Oncology Group Study

BACKGROUND: A serious complication associated with breast cancer treatment is the increased risk for development of therapy-related myeloid neoplasms (t-MN). METHODS: To determine whether dose-intensive adjuvant regimens for breast cancer induce genetic damage to hematopoietic stem cells, defined by...

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Detalhes bibliográficos
Main Authors: Slovak, Marilyn L., Bedell, Victoria, Lew, Danika, Albain, Kathy S, Ellis, Georgiana K., Livingston, Robert B., Martino, Silvana, Perez, Edith A., Sher, Dorie, Stock, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024910/
https://ncbi.nlm.nih.gov/pubmed/19851858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0597-5
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