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Clonal hematopoiesis and its emerging effects on cellular therapies
The accumulation of somatic mutations in hematopoietic stem cells during aging, leading to clonal expansion, is linked to a higher risk of cardiovascular mortality and hematologic malignancies. Clinically, clonal hematopoiesis is associated with a pro-inflammatory phenotype of hematopoietic cells an...
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| Udgivet i: | Leukemia |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8249428/ https://ncbi.nlm.nih.gov/pubmed/34215849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-021-01337-8 |
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