Clonal hematopoiesis and its emerging effects on cellular therapies

The accumulation of somatic mutations in hematopoietic stem cells during aging, leading to clonal expansion, is linked to a higher risk of cardiovascular mortality and hematologic malignancies. Clinically, clonal hematopoiesis is associated with a pro-inflammatory phenotype of hematopoietic cells an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: von Bonin, Malte, Jambor, Helena Klara, Teipel, Raphael, Stölzel, Friedrich, Thiede, Christian, Damm, Frederik, Kroschinsky, Frank, Schetelig, Johannes, Chavakis, Triantafyllos, Bornhäuser, Martin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249428/
https://ncbi.nlm.nih.gov/pubmed/34215849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-021-01337-8
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