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A molecular framework for temperature-dependent gating of ion channels
Perception of heat or cold in higher organisms is mediated by specialized ion channels whose gating is exquisitely sensitive to temperature. The physicochemical underpinnings of this temperature-sensitive gating have proven difficult to parse. Here, we took a bottom-up protein design approach, and r...
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| Udgivet i: | Cell |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405168/ https://ncbi.nlm.nih.gov/pubmed/25156949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.026 |
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