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Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels

Voltage-dependent potassium channels play a crucial role in electrical excitability and cellular signaling by regulating potassium ion flux across membranes. Movement of charged residues in the voltage-sensing domain leads to a series of conformational changes that culminate in channel opening in re...

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Bibliographic Details
Main Authors: Chowdhury, Sandipan, Haehnel, Benjamin M., Chanda, Baron
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210428/
https://ncbi.nlm.nih.gov/pubmed/25311635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411185
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