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Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain

Mutations that reduce glucose or insulin/insulin-like growth factor-I (IGF-I) signaling increase longevity in organisms ranging from yeast to mammals. Over the past 10 years, several studies confirmed this conserved molecular strategy of longevity regulation, and many more have been added to the com...

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Bibliografische gegevens
Gepubliceerd in:ScientificWorldJournal
Hoofdauteurs: Parrella, Edoardo, Longo, Valter D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: TheScientificWorldJOURNAL 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405166/
https://ncbi.nlm.nih.gov/pubmed/20098959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2010.8
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