Učitavanje...
Oncolytic virus expressing RANTES and IL-15 enhances function of CAR-modified T cells in solid tumors
We improved the migration and survival of chimeric antigen receptor (CAR)-modified T cells in solid tumors by combining CAR-T cells with an armed oncolytic virus. Local delivery of the chemokine RANTES and the cytokine IL-15 by the oncolytic virus enhanced the trafficking and persistence of the CAR-...
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| Izdano u: | Oncoimmunology |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404887/ https://ncbi.nlm.nih.gov/pubmed/25949885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.988098 |
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