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Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI(+)]

The yeast translation termination factor Sup35p, by aggregating as the [PSI(+)] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native...

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Publicat a:Front Microbiol
Autors principals: Gasset-Rosa, Fátima, Giraldo, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404881/
https://ncbi.nlm.nih.gov/pubmed/25954252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00311
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