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The Role of the N-Terminal Oligopeptide Repeats of the Yeast Sup35 Prion Protein in Propagation and Transmission of Prion Variants

The cytoplasmic [PSI(+)] determinant of Saccharomyces cerevisiae is the prion form of the Sup35 protein. Oligopeptide repeats within the Sup35 N-terminal domain (PrD) presumably are required for the stable [PSI(+)] inheritance that in turn involves fragmentation of Sup35 polymers by the chaperone Hs...

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Detalhes bibliográficos
Main Authors: Shkundina, Irina S., Kushnirov, Vitaly V., Tuite, Mick F., Ter-Avanesyan, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456247/
https://ncbi.nlm.nih.gov/pubmed/16272413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.048660
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