An Endogenous Nanomineral Chaperones Luminal Antigen and Peptidoglycan to Intestinal Immune Cells

In humans and other mammals, it is known that calcium and phosphate ions are secreted from the distal small intestine into the lumen. However, why this secretion occurs is unclear. Here, we show that the process leads to the formation of amorphous magnesium-substituted calcium phosphate nanoparticle...

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Detalhes bibliográficos
Publicado no:Nat Nanotechnol
Main Authors: Powell, Jonathan J, Thomas-McKay, Emma, Thoree, Vinay, Robertson, Jack, Hewitt, Rachel E, Skepper, Jeremy N, Brown, Andy, Hernandez-Garrido, Juan Carlos, Midgley, Paul A, Gomez-Morilla, Inmaculada, Grime, Geoffrey W, Kirkby, Karen J, Mabbott, Neil A, Donaldson, David S, Williams, Ifor R, Rios, Daniel, Girardin, Stephen E, Haas, Carolin T, Bruggraber, Sylvaine FA, Laman, Jon D, Tanriver, Yakup, Lombardi, Giovanna, Lechler, Robert, Thompson, Richard P H, Pele, Laetitia C
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404757/
https://ncbi.nlm.nih.gov/pubmed/25751305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2015.19
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