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Tolerogenic donor-derived dendritic cells risk sensitisation in vivo due to processing and presentation by recipient antigen-presenting cells
Modification of allogeneic dendritic cells (DCs) through drug treatment results in DCs with in-vitro hallmarks of tolerogenicity. Despite these observations, using murine MHC-mismatched skin and heart transplant models, donor-derived drug-modified DCs not only failed to induce tolerance but accelera...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736316/ https://ncbi.nlm.nih.gov/pubmed/23536635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200870 |
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