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Synthetic mimetics of the endogenous gastrointestinal nanomineral: Silent constructs that trap macromolecules for intracellular delivery

Amorphous magnesium-substituted calcium phosphate (AMCP) nanoparticles (75-150 nm) form constitutively in large numbers in the mammalian gut. Collective evidence indicates that they trap and deliver luminal macromolecules to mucosal antigen presenting cells (APCs) and facilitate gut immune homeostas...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Pele, Laetitia C., Haas, Carolin T., Hewitt, Rachel E., Robertson, Jack, Skepper, Jeremy, Brown, Andy, Hernandez-Garrido, Juan Carlos, Midgley, Paul A., Faria, Nuno, Chappell, Helen, Powell, Jonathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339085/
https://ncbi.nlm.nih.gov/pubmed/27478107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.07.008
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