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The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity
Mutation of the TRIM (tripartite motif)-NHL family members brat and mei-P26 perturb the differentiation of transit-amplifying progenitor cells resulting in tumour-like phenotypes. The NHL (named after the NCL1, HT2A and LIN41 repeat) domain is essential for their growth suppressive activity, and the...
Shranjeno v:
| izdano v: | Biochem J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404499/ https://ncbi.nlm.nih.gov/pubmed/24393003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131288 |
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