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Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis

The degeneration of motor neurons in amyotrophic lateral sclerosis (ALS) inevitably causes paralysis and death within a matter of years. Mounting genetic and functional evidence suggest that abnormalities in RNA processing and metabolism underlie motor neuron loss in sporadic and familial ALS. Abnor...

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Bibliografiske detaljer
Udgivet i:Neurotherapeutics
Hovedforfatter: Barmada, Sami J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404431/
https://ncbi.nlm.nih.gov/pubmed/25689976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0340-3
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