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A Novel Multiplexed, Image-Based Approach to Detect Phenotypes That Underlie Chromosome Instability in Human Cells

Chromosome instability (CIN) is characterized by a progressive change in chromosome numbers. It is a characteristic common to virtually all tumor types, and is commonly observed in highly aggressive and drug resistant tumors. Despite this information, the majority of human CIN genes have yet to be e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thompson, Laura L., McManus, Kirk J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404342/
https://ncbi.nlm.nih.gov/pubmed/25893404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123200
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