Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease.

Inhibitors of the human immunodeficiency virus type 1 (HIV-1) protease represent a promising addition to the available agents used to inhibit virus replication in a therapeutic setting. HIV-1 is capable of generating phenotypic variants in the face of a variety of selective pressures. The potential...

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Hauptverfasser: Kaplan, A H, Michael, S F, Wehbie, R S, Knigge, M F, Paul, D A, Everitt, L, Kempf, D J, Norbeck, D W, Erickson, J W, Swanstrom, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44043/
https://ncbi.nlm.nih.gov/pubmed/8202533
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