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T Cell-Extrinsic CD18 Attenuates Antigen-Dependent CD4(+) T cell Activation In Vivo

The β(2) integrins (CD11/CD18) are heterodimeric leukocyte adhesion molecules expressed on hematopoietic cells. The role of T cell-intrinsic CD18 in trafficking of naïve T cells to secondary lymphoid organs, and in antigen-dependent T cell activation in vitro and in vivo has been well-defined. Howev...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Wu, Xingxin, Lahiri, Amit, Sarin, Ritu, Abraham, Clara
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404034/
https://ncbi.nlm.nih.gov/pubmed/25801431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401328
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