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HSF-1 mediated cytoskeletal integrity determines thermotolerance and lifespan
The conserved transcription factor HSF-1 is essential to cellular stress resistance and organismal lifespan determination. The canonical function of HSF-1 is to regulate a network of molecular chaperones that maintain protein homeostasis during extrinsic environmental stresses or intrinsic age relat...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403873/ https://ncbi.nlm.nih.gov/pubmed/25324391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253168 |
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