Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores

Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to rely on their uptake by cancer cells expressing the...

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發表在:PLoS One
Main Authors: Liao-Chan, Sindy, Daine-Matsuoka, Barbara, Heald, Nathan, Wong, Tiffany, Lin, Tracey, Cai, Allen G., Lai, Michelle, D’Alessio, Joseph A., Theunissen, Jan-Willem
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403856/
https://ncbi.nlm.nih.gov/pubmed/25894652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124708
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