Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores

Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to rely on their uptake by cancer cells expressing the...

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Udgivet i:PLoS One
Main Authors: Liao-Chan, Sindy, Daine-Matsuoka, Barbara, Heald, Nathan, Wong, Tiffany, Lin, Tracey, Cai, Allen G., Lai, Michelle, D’Alessio, Joseph A., Theunissen, Jan-Willem
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403856/
https://ncbi.nlm.nih.gov/pubmed/25894652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124708
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