Φορτώνει......
Nimotuzumab enhances radiation sensitivity of NSCLC H292 cells in vitro by blocking epidermal growth factor receptor nuclear translocation and inhibiting radiation-induced DNA damage repair
BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a significant role in radiation resistance. There is evidence that EGFR nuclear translocation is associated with DNA double-strand breaks (DSB) repair. Nimotuzumab has shown the effect of radiosensitization in various ca...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Onco Targets Ther |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Dove Medical Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403694/ https://ncbi.nlm.nih.gov/pubmed/25926742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S77283 |
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